Gerald Coakley

Dr Gerald Coakley graduated from the Royal London Hospital Medical School in 1989.  After training in Nottinghamshire and London, he was awarded an Arthritis Research Campaign Fellowship, allowing him to carry out research in immunology and immunogenetics relating to Rheumatoid Arthritis and Felty's syndrome at Guy's Hospital, part of King's College School of Medicine. This led to his PhD in 2000.

He has worked as a Consultant at Queen Elizabeth Hospital, Woolwich since 2000, and has continued to work there since it merged with Lewisham Hospital to become the Lewisham & Greenwich NHS Trust in 2013.  He has continued to develop his interests in rheumatoid and other forms of inflammatory arthritis, but is also interested in the full range of musculoskeletal pain disorders, including fibromyalgia. He was Director of Medical Education from 2003 to 2013, and since 2013 has been Clinical Director for Dermatology, Neurology and Rheumatology at Lewisham & Greenwich.

Since 2001, he has been involved in the private sector care of people with Chronic Fatigue Syndrome / Myalgic Encephalomyelitis (CFS/ME), and runs a weekly private Fatigue Clinic at Keats House, St Thomas Street, London SE1.

In addition to these interests, he also has an interest in the evidence-based management of septic arthritis, in which capacity he has chaired a national guideline group and published numerous papers, including in the BMJ and The Lancet. He is member of the British Society for Rheumatology’s Education and Training Committee.

Blackheath Entries

Bupa Entries


Toxic epidermal necrolysis, pancytopenia and adult respiratory distress syndrome.  G Coakley, DA Isenberg.  British Journal of Rheumatology 1995;34:798.

Inflammatory muscle diseases: Theoretical aspects.  G Coakley, DA Isenberg. Rheumatology in Europe 1996;25/2:60-63.

MHC encoded TAP genes in rheumatic diseases.  G Coakley, JS Lanchbury. Editorial. British Journal of Rheumatology 1996;35:501-503.

Perspectives on HLA and disease.  G Coakley, MA Hall, JS Lanchbury.  Chapter in 'Autoimmunity and the Eye', M Zierhut, M Raizman, H Thiel (Eds), 1997.  Acolus Press BV.

IL-10 promoter polymorphisms in rheumatoid arthritis and Felty’s syndrome.  G Coakley, CC Mok, AH Hajeer, WER Ollier, D Turner, PJ Sinnott, IV Hutchinson, GS Panayi, JS Lanchbury.  British Journal of Rheumatology 1998;37:988-991.

Felty’s syndrome.  G Coakley, JS Lanchbury.  Review.  Current Medical Literature - Rheumatology.  Royal Society of Medicine.  1998;17/2:35-39.

Fas ligand and neutrophil apoptosis in Felty's and large granular lymphocyte syndromes. G Coakley, M Iqbal, GS Panayi, JS Lanchbury.  Arthritis & Rheumatism 1998 Abstract 661, 41(9) (Supplement).

A Fas promoter polymorphism at position –670 in the enhancer region does not confer susceptibility to Felty’s and large granular lymphocyte syndromes.  G Coakley, N Manolios, TP Loughran Jr, GS Panayi, JS Lanchbury.  Rheumatology.  1999;38:883-886.

Current perspectives on the genetics of rheumatoid arthritis.  M Fife, G Coakley, JS Lanchbury. Chapter in 'Rheumatoid arthritis: new frontiers in pathogenesis and treatment.' GS Firestein, GS Panayi and FA Wollheim (Eds.) 2000. Oxford University Press.

Genetic polymorphism of IL-12 p40 gene in immune-mediated disease.  MA Hall, E McGlinn, G Coakley, K Boki, A Young, D Middleton, E Kaklamani, H Moutsopoulos, TP Loughran Jr, WER Ollier, GS Panayi, JS Lanchbury.  Genes and Immunity 2000;1:219-224.  

MHC haplotypic associations in Felty’s and large granular lymphocyte syndromes are secondary to allelic association with HLA-DRB1*0401. G Coakley, D Brooks, M Iqbal, E Kondeatis, R Vaughan, TP Loughran Jr, GS Panayi, JS Lanchbury.  Rheumatology 2000;39:393-398.

CD8+CD57+ T cells from the healthy elderly suppress neutrophil development in vitro: implications for the neutropenia of Felty’s and large granular lymphocyte syndromes.
G Coakley, M Iqbal, D Brooks, GS Panayi, JS Lanchbury.  Arthritis & Rheumatism 2000;43(4):834-843.

Sjogren's syndrome associated T cell large granular lymphocyte leukemia: a possible common etiopathogenesis.  J Rheumatol. 2002 Aug;29(8):1803

Autoantibodies against granulocyte-macrophage colony stimulating factor and interleukin-3 are rare in patients with Felty's syndrome. Hellmich B, Ciaglo A, Schatz H, Coakley G. Ann Rheum Dis.  2004;63(7):862-6.

Analysis of predictors of success in the MRCP (UK) PACES examination in candidates attending a revision course. Bessant R, Bessant D, Chesser A, Coakley G.
Postgrad Med J.2006;82(964):145-9.

Acute hot joint.  Mathews CJ, Coakley G. British Journal of Hospital Medicine (Lond). 2006;67(5):232-4.

BSR & BHPR, BOA, RCGP and BSAC guidelines for management of the hot swollen joint in adults.  Coakley G, Mathews C, Field M et al. Rheumatology (Oxford). 2006;45(8):1039-41

Guideline for the management of the hot swollen joint in adults with a particular focus on septic arthritis.  Weston V, Coakley G.  Journal of Antimicrobial Chemotherapy. 2006;58(3):492-3.

Polyarticular septic arthritis. Christodoulou C, Gordon P, Coakley G. British Medical Journal. 2006;25;333(7578):1107-8

Guidelines causing iatrogenic diseases?: reply. Coakley G, Mathews C, Field M et al.  Rheumatology (Oxford). 2007;46(4):723-4

Management Of Septic Arthritis – A Systematic Review. Mathews CJ, Kingsley G, Field M, Jones A, Weston VC, Phillips M, Walker D, Coakley G.  Annals of Rheumatic Disease.  2007;66(4):440-5.

Future Management of Septic Arthritis.  Mathews CJ, Weston VC, Kingsley G, Coakley G.  Future Rheumatology.  2008:3(1);43-50.

Management of septic arthritis: a systematic review. Mathews CJ, Kingsley G, Field M, Jones A, Weston VC, Phillips M, Walker D, Coakley G . Postgraduate Medical Journal. 2008; 84: 265-270.

Septic arthritis: current diagnostic and therapeutic algorithm.  Mathews CJ, Coakley G.  Current Opinion in Rheumatology.  2008:20;457-462.

Septic Arthritis. Coakley G, Mathews CJ.  BMJ Point-of-Care 2008;

The treatment and care of hot swollen joints.  Al-Sharkachi I, Coakley G.  Rheumatology in Practice.  2009;7(2);7-9.  

Felty’s syndrome.  Coakley G, Hull D.  BMJ Point-of-Care 2009;

Seminar: Bacterial septic arthritis in Adults.  Mathews CJ, Field M, Jones A, Weston VC, Coakley G.  Lancet. 2010:375;846-855.

Let off the leash: kala-azar following the use of tumour necrosis factor antibodies.  BMJ Case Reports 2010;10.1136/bcr.04.2010.2878

What’s new in the management of bacterial septic arthritis? Chander S, Coakley G.  Current Infectious Disease Reports. 2011:13;478-484.

Synovial fluid tests. Al-Shakarchi, I., Coakley, G. Medicine 2014:42(4);202-204

Surgery is not always best for lumbar spinal stenosis. Coakley G. BMJ. 2016 Aug 23;354.

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